Background: To evaluate the efficacy and safety of abiraterone acetate (AA) plus prednisone compared with\nprednisone alone in Asian patients with chemotherapy-naive metastatic castration-resistant prostate cancer\n(mCRPC), and to identify predictive factors.\nMethods: We reviewed the medical records of 60 patients with chemotherapy-naive mCRPC at Renji Hospital who\nwere treated with AA plus prednisone (n = 43) or prednisone alone (n = 17). All patients were assessed for prostatespecific\nantigen (PSA) response, PSA progression-free survival (PSA PFS), radiographic progression-free survival (rPFS),\nand overall survival (OS). The ability of several parameters to predict PSA PFS, rPFS, and OS was studied....................
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